PRODUCT DETAILS

About Avonza Tablet

EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Uses of Avonza Tablet

Hiv infection.

Medicinal Benefits of Avonza Tablet

EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil fumarate. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication. EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE also increases the CD4 cell (white blood cells that protect against infection) count in your blood.

Directions for Use

EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is available in form of tablets. Take this EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is to be taken empty stomach.

Side Effects of Avonza Tablet

• Headache
• Dizziness
• Nausea
• Insomnia (difficulty in sleeping)
• Weakness
• Depression
• Cough
• Diarrhoea
• Impaired concentration
• Abnormal dreams
• Fatigue
• Nasal congestion (stuffy nose)
• Pain

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

It is not recommended to take EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE if you are allergic to any contents of it. Before taking EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), CNS disorders, hypercholesterolemia, and kidney disease. Inform your doctor if you are pregnant or breastfeeding. EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE should not be given to children below 2 years of age. EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE should be used with caution in elderly patients. Alcohol consumption may increase the risk of side-effects. EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis.

Drug Interactions

Drug-Drug Interaction:

EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may interact with drugs like anticancer (cisplatin), anti-depressant (citalopram), anti-fungal (fluconazole), antibiotics (gentamicin, ciprofloxacin, azithromycin, tobramycin), antimetabolites (methotrexate), potassium-sparing diuretics (amiodarone), anti-platelet drug (aspirin).

Drug-Disease Interaction:

EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE should not be used in patients with liver disease, kidney diseases, hepatitis B or C (liver infections), CNS disorders, heart diseases, hypercholesterolemia, bone disorders, lactic acidosis, immune reconstitution syndrome

Safety Advice

ALCOHOL

• Consumption of alcohol may increase the risk of side-effects.

PREGNANCY

• EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE.

BREAST FEEDING

• EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

DRIVING

• EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

LIVER

• EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

KIDNEY

• EFAVIRENZ+LAMIVUDINE+TENOFOVIR DISOPROXIL FUMARATE should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.